| 21/5/2025 | Tottenham beat Manchester United 1-0 in the Europa League final in Bilbao and win their first trophy since 2008. Ange Postekoglou becomes the first Greek manager to coach a team at a European final and the first to win a European trophy. |
| 21/5/2023 | 39-year-old Greek race walker Antigoni Drisbioti wins the gold medal in the 20 km walk at the European Championships in Podebrady, Czech Republic. The holder of the Panhellenic record finished ahead of her competitors in 1 hour, 29 minutes and 17 seconds, achieving the third-best performance of her career. |
| 21/5/2023 | Real Madrid defeats Olympiakos 79-78 in the Euroleague final held in Kaunas, Lithuania and is crowned European champion. Two days earlier, Olympiacos defeating Monaco 76-62 in the first semi-final, with a stunning 27-2 third quarter. Edy Tavares will be crowned Final Four MVP. |
| 21/5/2021 | 24-year-old Greek swimmer Apostolos Christou finishes third in the 100 meters backstroke final with 52.97 at the 2021 LEN European Aquatics Championships, winning bronze. |
| 21/5/2006 | Anastasia Kostaki becomes the first basketball player from Greece to wear –in a formal match- the shirt of the 4-time champions WNBA Comets against San Antonio Silver Stars in front of 11.000 fans at Houston. She played for 18 minutes, scoring 10 points wearing the shirt No. 55 |
| 21/5/2005 | Olympiacos FC wins the National Football Cup (the 21st in the club’s history) by defeating Aris Salonica with 3-0 at Patras |
| 21/5/1999 | 19 year-old Kokkina Deldekovski receives a deadly punch from Artur Kevorian at the ''Tofalia'' international meeting in Patras |
| 21/5/1997 | Schalke win the UEFA Cup after defeating Inter on penalty kicks - their first european title in 93 years |
| 21/5/1997 | Olympiacos win the championship after beating AEK 68-53. It is the third title Olympiacos win this season (along with the Greek Cup and the Euroleague title) |
| 21/5/1997 | 19 year-old David Connolly of Watford becomes the youngest football player to score a hat trick for N. Ireland in their victory over Lichtenstein (5-0) for the World Cup qualifying round |
| 21/5/1996 | 20 year-old Andy Farrell becomes the youngest captain of England's rugby national team |
| 21/5/1991 | Nikos Galis (1.120) is voted best Greek basketball player ever by Greek journalists, followed by Panagiotis Giannakis (1.108), Panagiotis Fassoulas (1.101), Vassilis Goumas (916) and Fanis Christodoulou (913). Giannis Ioannidis is voted best Greek coach and Aris Salonica best team |
| 21/5/1971 | Chelsea win the European Cup Winners Cup after defeating Real Madrid 2-1. On their way to the final Chelsea had eliminated Aris Salonica (1-1 and 5-1) |
| 21/5/1967 | After being interrupted for 34 days, the football championship begins with matches of matchday 26. Matchday 25 was played on 16/4/1967 but 5 days later the military coup took place so games were postponed until a safer date. |
| 21/5/1927 | Charles Augustus Lindbergh concludes his Orteig Prize-winning solo non-stop flight from Roosevelt Field in New York City to Le Bourget Field in Paris in the single-seat, single-engine monoplane “Spirit of St. Louis” |
| 21/5/1904 | French journalist Robert Guerin persuades the delegates of France and 7 other countries (Belgium, Denmark, Germany, Spain, Sweden, Switzerland, Holland) to establish FIFA (Federation Internationale de Football Association) |
| 21/5/1891 | James John Corbett and Peter Jackson fight 61 rounds to no decision |
